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Biopharma Chromatography Systems Market Report
“The biopharma chromatography systems market size was valued at USD 4.0 billion in 2025 and offers robust growth opportunities for market stakeholders. With the market expected to grow at a CAGR of 9.4% (2026-2030), annual sales are projected to reach USD 6.0 billion by 2030, underscoring the accelerating shift toward biologics-driven downstream purification across global biopharma manufacturing.”
“The next phase of market growth will be driven by the rapid expansion of biologics pipelines-particularly monoclonal antibodies, GLP-1 receptor agonists, and cell & gene therapies-alongside the growing outsourcing wave to contract manufacturing organizations (CMOs). The key segments for decision-makers can be the CMO end-user type, liquid chromatography as the dominant media type, and North America as the leading region.”
“The biopharma chromatography systems industry is moving decisively from research-scale use toward commercial-scale manufacturing. The biologics boom is the central engine, with monoclonal antibodies representing the largest class of biologic therapeutics. Every commercial mAb requires multiple chromatographic purification steps, primarily protein A affinity capture followed by polishing runs on ion exchange and size exclusion systems.”
“We are also seeing a major biopharma chromatography systems market trend, with single-use chromatography platforms gaining rapid adoption in CMO settings. These systems minimizes cross-contamination risk, slash cleaning validation costs, and enable flexible multi-product manufacturing-exactly what the current biologics contract manufacturing boom demands. Thermo Fisher's September 2025 completion of its USD 4.0 billion acquisition of Solventum's Purification & Filtration Business signals just how strategically critical downstream purification infrastructure has become. When you combine this consolidation trend with the surge in GLP-1 drug purification requirements and continuous bioprocessing adoption, the market trajectory is strongly positive well into the decade.”
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